• br Materials and methods br

  2022-05-17

  

  Materials and methods Results Discussion The major findings of the present study are that: 1) the response to inverse agonists may be crossregulated by the activation of either Eeyarestatin I H1 or H2 receptors, 2) histamine H1 and H2 receptor inverse agonists crossdesensitize the receptor

• Hippo pathway proteins could synergistically regulate germ c

  2022-05-17

  

  Hippo pathway proteins could synergistically regulate germ cell development with some specific receptors. Kassab et al. [27] found that epidermal growth factor (EGF) receptor was localized in testicular germ STF 31 and played important roles in bovine spermatogenesis. Likewise, insulin-like growth

• Among the HER mutations reported in this study the

  2022-05-17

  

  Among the HER2 mutations reported in this study, the JMD mutant R678Q is the third most recurrent HER2 mutation. Basic residues (such as arginine) play an important role in anchoring TMD helices of single transmembrane proteins to the bilayer (Gleason et al., 2013, Hristova and Wimley, 2011, Kim et 

• HO acted as an intracellular defender against oxidative

  2022-05-17

  

  HO-1 acted as an intracellular defender against oxidative stress-induced cell damage. To elucidate the effects of HO-1 in ropivacaine-induced cytotoxicity in neuronal cells, HO-1 activity was inhibited using a specific HO-1 inhibitor zinc protoporphyrin, ZnPP. Our results indicate that ZnPP treatmen

• br Authors contribution br Funding sources This study

  2022-05-17

  

  Authors' contribution Funding sources This study was supported by CDC intramural funding. Publication costs are funded by an internal program of CDC. MAT was supported by funds from the Association of Public Health Laboratories and CDC (APHL–CDC) Bioinformatics Fellowship Program. Competing

• A common principle to ameliorate underquantification because

  2022-05-17

  

  A common principle to ameliorate underquantification because of primer or probe mismatching is to employ multiple targets for detection or quantification of blood borne viruses [14]. Dual targeting real time PCRs have become common for quantification of HIV-1 [15], [16]. In a recent paper arguing fo

• Glutathione S transferases constitute a family of enzymes in

  2022-05-17

  

  Glutathione-S-transferases constitute a family of enzymes involved in the detoxification of xenobiotics, signalling cascades and serving as ligandins or/and catalyzing the conjugation of various chemicals and drugs [53]. The present finding indicates significant increase in GST activity in the brain

• br Materials and methods br

  2022-05-17

  

  Materials and methods Results Discussion Reduced glutathione is considered to be one of the important regulators of REDOX balance in the biological system. The cellular concentration of 4-HNE under physiological conditions ranges from 0.1 to 3μM and has no detrimental effect in the biologic

• Finally our work showed that HAART resulted in significant

  2022-05-17

  

  Finally, our work showed that HAART resulted in significant inter-individual variability among DEGs, which reflected the BCECF-AM in HIV-affected human gene expressions (Fig. 1, Fig. 2, Fig. 3, Fig. 4). These observations also highlighted the importance of determining common as well as personal spe

• br Other Functions of HCA Receptors

  2022-05-17

  

  Other Functions of HCA Receptors HCA receptors, in particular HCA1, are expressed in various primary tumor Furosemide receptor 77, 78, 79. This is of interest, as most solid tumors show increased glucose uptake and lactate formation even under normoxic conditions, with lactate concentrations in

• Finally our data found that the EBV dUTPase protein

  2022-05-17

  

  Finally, our data found that the EBV dUTPase protein modulates tryptophan, serotonin, and DA metabolism and use in vitro and in vivo. The EBV dUTPase may alter kynurenine catabolism in microglia in vitro, suggesting that there is an increase synthesis of quinolinic acid. Quinolinic acid, an agonist

• br Introduction Cell surface receptors are central to

  2022-05-17

  

  Introduction Cell surface receptors are central to the interaction of cells with their surroundings and play an important role in determining functional responses. These receptors are integral membrane proteins responsible for the binding of extracellular signaling molecules and transduction into

• The PCR based analysis of TRECs in general

  2022-05-17

  

  The PCR-based analysis of TRECs in general is laborious, technically challenging and comparison of results obtained in different laboratories is difficult as different normalization standards exist. Moreover the analysis is restricted to analysis of cell populations (Douek et al., 1998; Jamieson et

• Ironically another series of studies examining the role of

  2022-05-16

  

  Ironically, another series of studies examining the role of EAATs in CNS injury and disease suggest that under some pathological conditions, the operation of the EAATs is not protective, but actually contributes to the excitotoxic process (Rossi et al., 2000). The transporters do so by serving as th

• The development of immobilization techniques for glucosidase

  2022-05-16

  

  The development of immobilization techniques for β-glucosidase offers a potential way to enable its reuse several times [13]. The aim of immobilization is to trap the enzyme within or on the surface of an insoluble material with retention of its catalytic activity [14]. The immobilization strategy a

15350 records 462/1024 page Previous Next First page 上5页 461462463464465 下5页 Last page