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The objective of the present work is
2021-08-02

The objective of the present work is to search for the optimum blend when 12.5–50% metakaolin is substituted by RHA and reacted with 10 M sodium hydroxide solution to produce geopolymers. It was hypothesized that the amorphous Famprofazone receptor from RHA will increase the Si/Al ratio of the mix
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RHA is an agricultural by product obtained
2021-08-02

RHA is an agricultural by-product obtained from the burning process of rice hull [7], [8]. Rice hull is the outer layer of paddy grain. About 20% of rice hull converts into RHA when it is burnt during the Gabapentin sale generation processes [8], [9]. If RHA produced at less than 700 °C, it chemica
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Enolases are among the most abundantly expressed cytosolic p
2021-07-31

Enolases are among the most abundantly expressed cytosolic proteins. They are metalloenzymes that catalyze the conversion of 2-phosphoglycerate to phosphoenolpyruvate [18]. Eubacteria and archaebacteria have a single enolase gene (reviewed in [19]). Despite the lack of signal peptides or cognate pro
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Immunofluorescence assays were performed to localize the enz
2021-07-31

Immunofluorescence assays were performed to localize the enzyme during growth and differentiation to further characterize Giardia E1. As stated before, the assays showed that the Physcion generated recognized specific E1 forms (E1-114, E1-90 and E1-67 with anti-gNTE1; and E1-47 with anti-gE1CT); th
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br Other factors regulating DNA PKcs Recent work in
2021-07-31

Other factors regulating DNA-PKcs Recent work in the field has also focused on factors that regulate NHEJ and NHEJ factors, in particular proteins that modulate DNA-PKcs. In this section we will highlight a number of factors which have been found to regulate DNA-PKcs. DNA-PKcs phosphorylation at
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The first purpose of the current study was to characterize
2021-07-31

The first purpose of the current study was to characterize a standardized experimental model of postprandial hyperlipidemia in various rodent species. To our knowledge this study provides the most comprehensive and systematic evaluation of rodent models of postprandial hyperlipidemia to date. We ada
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Interferon IFN induces formation of a
2021-07-31

Interferon (IFN)-γ induces formation of a heterotetrameric, IFN-gamma-activated inhibitor of translation (GAIT) complex in human monocytic neurotensin receptor (Mazumder et al., 2003a, Sampath et al., 2004). The complex binds a bipartite stem-loop element in the 3′UTR of vascular endothelial growth
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br Materials and methods br Acknowledgments This
2021-07-31

Materials and methods Acknowledgments This research was supported by funding from University of California Irvine to H.U.B. Introduction Oral squamous cell carcinoma (OSCC) is the fourth major cause of mortality among men in Taiwan and its incidence rates continue to rise annually. OSCC is
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Metabolism Compound Library synthesis br Conclusions The pre
2021-07-31

Conclusions The present study demonstrated that CuE possesses strong hepatotoxicity. CuE is not only a mechanism-based inhibitor of human CYP3A4, but also inhibits P-gp activity in vitro. In whole animal studies, CuE induces CYP3A and P-gp after a long-term treatment but inhibits the activities o
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The COMT gene maps to chromosome q Grossman et al
2021-07-31

The COMT gene maps to chromosome 22q11.2 (Grossman et al., 1992) and has two protein isoforms. The differences between S-COMT and longer MB-COMT are in the N-termini, which use alternative translation initiation sites and promoters. These two isoforms display different affinity and capacity for COMT
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br Experiments br Numerical simulations br Discussion br Con
2021-07-30

Experiments Numerical simulations Discussion Conclusions By large-caliber PELE with various d/D against RHA plate at low velocity of 415 m s−1, impact experiments against 30 mm RHA target were carried out. Numerical simulations were also conducted to monitor progress of PELE expansion an
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br Results br Discussion Our UbV library was
2021-07-30

Results Discussion Our UbV library was originally designed to develop inhibitors of deubiquitinases (Ernst et al., 2013). Recently, we showed that UbVs could exhibit multiple binding modes and mechanisms to modulate HECT E3 activity (Zhang et al., 2016)—one set occupied the HECT domain E2-bind
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br RING dimerization RING type domains
2021-07-30

RING dimerization RING-type domains are found in many different structural contexts. While many exist as single-chain Tirapazamine (Fig. 3A), a notable feature of RING-type E3s is their tendency to form homodimers and heterodimers (Fig. 3C–F). Homodimeric RING-type E3s include cIAP, RNF4, BIRC7 (
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ICT is a product of
2021-07-30

ICT is a product of icariin via the metabolism of intestinal bacteria with estrogen-like activities [33]. ICT as a bone-protecting agent can enhance osteoblast differentiation while suppressing osteoclastic differentiation in vitro [19], and stimulate osteogenic differentiation and inhibit adipogene
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Yeast Extract We have compared the potency of a series
2021-07-30

We have compared the potency of a series of DNA-directed alkylating agents, including N-mustard-acridine, N-mustard-quinoline, and N-mustard-quinazoline conjugates previously synthesized in our laboratory [7], [13], and currently used drugs (oxaliplatin, cisplatin, or 5-FU) for the treatment of CRC
 
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